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Introduction What's sickle cell disease (SCD)? What causes sickle cell anemia? What are the symptoms of sickle cell anemia? What are the remedies for sickle cell anemia? What's the prognosis for sickle cell anemia? What's sickle cell illness (SCD)? Sickle cell anemia (sickle cell disease) is a disorder of the blood brought on by inherited abnormal hemoglobin (the oxygen-carrying protein inside the pink blood cells). The abnormal hemoglobin causes distorted (sickled showing below a microscope) purple blood cells. The sickled crimson blood cells are fragile and liable to rupture. When the number of purple blood cells decreases from rupture (hemolysis), BloodVitals SPO2 anemia is the result. This situation is known as sickle cell anemia. The irregular sickled cells can also block blood vessels inflicting tissue and organ harm and pain. Sickle cell anemia is one of the most common inherited blood anemias. The disease primarily affects Africans and real-time SPO2 tracking African Americans. It's estimated that in the United States, some 90,000 to 100,000 Americans are stricken with sickle cell anemia.

Overall, current estimates are that one in 500 U.S. African American births is affected by sickle cell anemia. What causes sickle cell anemia? Sickling of the red blood cells in patients with sickle cell anemia results in cells of abnormal form and diminished flexibility. The sickling is promoted by situations associated with low oxygen ranges, elevated acidity, or BloodVitals insights low volume (dehydration) of the blood. These circumstances can happen due to damage to the physique's tissues, dehydration, or anesthesia. Certain organs are predisposed to decrease oxygen levels or BloodVitals insights acidities, corresponding to when blood strikes slowly via the spleen, liver, or BloodVitals SPO2 kidney. In addition, BloodVitals insights organs with particularly excessive metabolism charges (such because the mind, muscles, and the placenta in a pregnant girl with sickle cell anemia) promote sickling by extracting more oxygen from the blood. These conditions make these organs inclined to harm from sickle cell anemia. What are the signs of sickle cell anemia? Virtually all of the main signs of sickle cell anemia are the direct result of the abnormally formed, sickled crimson blood cells blocking the flow of blood that circulates by way of the tissues of the body.

The tissues with impaired circulation undergo harm from a scarcity of oxygen. Damage to tissues and organs of the body may cause extreme disability in patients with sickle cell anemia. The patients endure episodes of intermittent "crises" of variable frequency and severity, depending on the degree of organ involvement. Many features typically happen in certain age groups. Infants with sickle cell anemia don't develop signs in the first few months of life as a result of the hemoglobin produced by the creating fetus (fetal hemoglobin) protects the crimson blood cells from sickling. This fetal hemoglobin is absent within the red blood cells that are produced after beginning so that by 5 months of age, real-time SPO2 tracking the sickling of the purple blood cells is distinguished and symptoms begin. Symptoms in adults usually are intermittent ache episodes as a consequence of harm of bone, muscle, or internal organs. Sickle cell anemia is prompt when the abnormal sickle-shaped cells within the blood are recognized underneath a microscope.

Testing is usually performed on a smear of blood using a particular low-oxygen preparation. This is referred to as sickle prep. Other prep tests may also be used to detect abnormal hemoglobin S, together with solubility checks carried out on tubes of blood solutions. The disease may be confirmed by specifically quantifying the forms of hemoglobin present utilizing hemoglobin electrophoresis. Prenatal analysis (before start) of sickle cell anemia is feasible utilizing amniocentesis or chorionic villus sampling. The sample obtained is then tested for painless SPO2 testing DNA analysis of the fetal cells. The hemoglobin electrophoresis take a look at precisely identifies the hemoglobin in the blood by separating them. The separation of the completely different hemoglobin is possible due to the unique electrical expenses they every have on their protein surfaces, causing them each to maneuver characteristically in an electrical subject as tested in the laboratory. What are the therapies for sickle cell anemia? Fatigue is a standard symptom in persons with sickle cell anemia.

Sickle cell anemia causes a chronic form of anemia, which may result in fatigue. The sickled purple blood cells are prone to breakage (hemolysis) which causes decreased red blood cell life span (the traditional life span of a red blood cell is one hundred twenty days). These sickled pink blood cells are simply detected with a microscope examination of a smear of blood on a glass slide. Typically, the positioning of pink blood cell manufacturing (bone marrow) works time beyond regulation to produce these cells rapidly, attempting to compensate for BloodVitals insights his or her destruction in the circulation. Occasionally, BloodVitals insights the bone marrow suddenly stops producing purple blood cells, which causes a very extreme type of anemia (aplastic crises). Aplastic crises may be promoted by infections that in any other case would seem much less important, together with viruses of the stomach and BloodVitals insights bowels and the flu (influenza). Sickle cell anemia tends to stabilize without specific treatments. The diploma of anemia is outlined by the measurement of the blood hemoglobin level. Hemoglobin is the protein molecule in crimson blood cells that carries oxygen from the lungs to the physique's tissues and returns carbon dioxide from the tissues to the lungs.